1,3,4-OXADIAZOLE DERIVATIVE ATTENUATES CHRONIC CONSTRICTION INJURY INDUCED NEUROPATHIC PAIN: A COMPUTATIONAL, BEHAVIORAL, AND MOLECULAR APPROACH

1,3,4-Oxadiazole Derivative Attenuates Chronic Constriction Injury Induced Neuropathic Pain: A Computational, Behavioral, and Molecular Approach

The production and up-regulation of inflammatory mediators are contributing factors for the development and maintenance of neuropathic pain.In the present study, the post-treatment of synthetic 1,3,4 oxadiazole derivative (B3) for its neuroprotective potential in chronic constriction injury-induced neuropathic pain was applied.In-silico studies wer

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Serious Games, Mental Images, and Participatory Mapping: Reflections on a Set of Enabling Tools for Capacity Building

Increasing complexity of societal questions requires participatory processes that engage with capable participants.We adopted Horellis’ stance on participation as not an isolated event but a constant communication between different groups that can be assured by using enabling tools.We applied the Capability Approach to frame a capacity-buildi

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DETERMINATION OF ANTI-ARTHRITIC ACTIVITY OF THE LEAVES EXTRACTS OF PROSOPIS JULIFLORA (SW) DC BY USING IN VITRO METHOD

Rheumatoid arthritis (RA) is an autoimmune inflammatory condition with an unknown aetiology that causes cartilage and bone to erode.The ineffectiveness and side effects of the current therapeutic agents, such as glucocorticoids, disease-modifying anti-rheumatic drugs, and non-steroidal anti-inflammatory drugs (NSAIDs), highlight the need for findin

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